A hierarchy of selection pressures determines the organization of the T cell receptor repertoire

Keyphrases

• Aged Mice 100%
• CD8+ 100%
• Selection Pressure 100%
• T-cell Receptor Repertoire 100%
• T Cells 50%
• Adult Mice 50%
• Divergence 50%
• Nucleotide Sequence 50%
• Complementarity-determining Region 3 (CDR3) 50%
• Statistical Properties 50%
• CD4+ 50%
• Older Adults 50%
• V Genes 50%
• Infected Mice 50%
• Naïve Cells 50%
• T Cell Subsets 50%
• Somatic Recombination 50%
• Frequency Distribution 50%
• Statistical Features 50%
• Acute Infection 50%
• Antigen Exposure 50%
• K-mer Frequency 50%
• Quantitative Framework 50%
• CD4+ Regulatory T Cells 50%
• Effector Evolution 50%
• Limited Overlap 50%
• Immunological Processes 50%

Immunology and Microbiology

• Lineages 100%
• CD4 100%
• T Cell Receptor 100%
• CD8 100%
• T Cell 50%
• Nucleotide Sequence 50%
• Regulatory T Cell 50%
• T Cell Subset 50%
• Mitotic Recombination 50%