Cancer microbiome

Laurence Zitvogel; Ravid Straussman; Gregory D. Sepich-Poore; Rob Knight; Iliyan D. Iliev; Cynthia L. Sears; Susan Bullman; Christian Jobin; Hassane M. Zarour

doi:10.1016/j.ccell.2022.11.007

Cancer microbiome

Laurence Zitvogel, Ravid Straussman, Gregory D. Sepich-Poore, Rob Knight, Iliyan D. Iliev, Cynthia L. Sears, Susan Bullman, Christian Jobin, Hassane M. Zarour

Department of Molecular Cell Biology

Research output: Contribution to journal › Comment/debate › peer-review

4 Citations (Scopus)

Abstract

Tumors contain viruses, bacteria, and fungi, collectively known as the microbiome. Here, experts discuss how the field evolved from reporting systemic effects of gut microbiota on the immune system, metastasis, and therapy response to studying intratumoral microbiome, and outline the future challenges and opportunities in modulating microbiota for therapeutic benefit.

Original language	English
Pages (from-to)	1443-1447
Number of pages	5
Journal	Cancer Cell
Volume	40
Issue number	12
DOIs	https://doi.org/10.1016/j.ccell.2022.11.007
Publication status	Published - 12 Dec 2022

Funding

Work related to the text by R.S. was funded by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement no. 818086). G.D.S.-P. and R.K. wish to acknowledge the patients and their families who have helped contribute toward a better understanding of this field. R.K. is funded in part by grants from the National Cancer Institute (R01 CA255206 and U24 CA248454) and by the National Institutes of Health (NIH DP1AT010885).

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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10.1016/j.ccell.2022.11.007

Cite this

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title = "Cancer microbiome",

abstract = "Tumors contain viruses, bacteria, and fungi, collectively known as the microbiome. Here, experts discuss how the field evolved from reporting systemic effects of gut microbiota on the immune system, metastasis, and therapy response to studying intratumoral microbiome, and outline the future challenges and opportunities in modulating microbiota for therapeutic benefit.",

author = "Laurence Zitvogel and Ravid Straussman and Sepich-Poore, \{Gregory D.\} and Rob Knight and Iliev, \{Iliyan D.\} and Sears, \{Cynthia L.\} and Susan Bullman and Christian Jobin and Zarour, \{Hassane M.\}",

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journal = "Cancer Cell",

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T1 - Cancer microbiome

AU - Zitvogel, Laurence

AU - Straussman, Ravid

AU - Sepich-Poore, Gregory D.

AU - Knight, Rob

AU - Iliev, Iliyan D.

AU - Sears, Cynthia L.

AU - Bullman, Susan

AU - Jobin, Christian

AU - Zarour, Hassane M.

PY - 2022/12/12

Y1 - 2022/12/12

N2 - Tumors contain viruses, bacteria, and fungi, collectively known as the microbiome. Here, experts discuss how the field evolved from reporting systemic effects of gut microbiota on the immune system, metastasis, and therapy response to studying intratumoral microbiome, and outline the future challenges and opportunities in modulating microbiota for therapeutic benefit.

AB - Tumors contain viruses, bacteria, and fungi, collectively known as the microbiome. Here, experts discuss how the field evolved from reporting systemic effects of gut microbiota on the immune system, metastasis, and therapy response to studying intratumoral microbiome, and outline the future challenges and opportunities in modulating microbiota for therapeutic benefit.

UR - https://www.scopus.com/pages/publications/85143977928

U2 - 10.1016/j.ccell.2022.11.007

DO - 10.1016/j.ccell.2022.11.007

M3 - Comment/debate

C2 - 36513044

SN - 1535-6108

VL - 40

SP - 1443

EP - 1447

JO - Cancer Cell

JF - Cancer Cell

IS - 12

ER -

Cancer microbiome

Abstract

Funding

All Science Journal Classification (ASJC) codes

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