Abstract
Encoding of real-life episodic memory commonly involves integration of information as the episode unfolds. Offline processing immediately following event offset is expected to play a role in encoding the episode into memory. In this study, we examined whether distinct human brain activitytime-lockedtotheoffsetofshortnarrativeaudiovisualepisodes could predict subsequent memory for the gist of the episodes. We found that a set of brain regions, most prominently the bilateral hippocampus and the bilateral caudate nucleus, exhibit memory-predictive activity time-locked to the stimulus offset. We propose that offline activity in these regions reflects registration to memory of integrated episodes.
| Original language | English |
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| Pages (from-to) | 9032-9042 |
| Number of pages | 11 |
| Journal | Journal of Neuroscience |
| Volume | 31 |
| Issue number | 24 |
| DOIs | |
| Publication status | Published - 15 Jun 2011 |
Funding
U.S.-Israel Binational Science Foundation; Nella and Leon Benoziyo Center for Neurological DiseasesThis work was supported by grants from the U.S.-Israel Binational Science Foundation and The Nella and Leon Benoziyo Center for Neurological Diseases (Y.D.). We are grateful to Ilan Dinstein, Micah Edelson, Maytal Flitter, Orit Furman, Kelly Ludmer, Avi Mendelsohn, Alex Pine, Uri Nili, Shiri Ron, and Amnon Yacoby for valuable comments. We also thank Edna Furman-Haran, Fanny Attar, and Nachum Stern from the Norman and Helen Asher Center for Brain Imaging at the Weizmann Institute.
All Science Journal Classification (ASJC) codes
- General Neuroscience