Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

Keyphrases

• Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) 100%
• Single-cell RNA Sequencing (scRNA-seq) 100%
• Regulatory Circuit 100%
• Pooled Screening 100%
• Crisps 100%
• Dendritic Cells 66%
• Redundancy 66%
• Cellular Heterogeneity 33%
• Multicellular Organism 33%
• Control Cell 33%
• Comprehensive Approach 33%
• Transcriptome 33%
• Massively Parallel 33%
• Monocytes 33%
• Differential Function 33%
• Cell Lineage 33%
• Cell Response 33%
• Opposing Effects 33%
• Cellular Diversity 33%
• Monocyte-derived Macrophages 33%
• Innate Immunity 33%
• RelA 33%
• Integration Method 33%
• Circuit Control 33%
• Interferon Regulatory Factor 8 (IRF8) 33%
• CEBPB 33%
• Unbiased Approach 33%

Biochemistry, Genetics and Molecular Biology

• CRISPR 100%
• RNA Sequencing 100%
• Dendritic Cell 100%
• Immunity 100%
• Infectious Agent 50%
• Macrophage 50%
• Transcriptome 50%
• RNA Sequence 50%
• Cell Lineage 50%
• Innate Immunity 50%
• Genomics 50%
• Carisoprodol 50%

Immunology and Microbiology

• RNA Sequencing 100%
• Clustered Regularly Interspaced Short Palindromic Repeat 100%
• Dendritic Cell 100%
• Immunity 100%
• RNA Sequence 50%
• Infectious Agent 50%
• Transcriptome 50%
• Macrophage 50%
• Cell Lineage 50%
• Innate Immune System 50%