Erratum: Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature (vol 25, pg 1219, 2016)

Jeffrey I. Boucher*, Daniel N. A. Bolon, Dan S. Tawfik

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

2 Citations (Scopus)

Abstract

Protein Science, 27: 1219–1226. doi:10.1002/pro.2928 Equation 1 has been erroneously printed, and should read as follows: (Formula presented.) whereby f is the fraction of an allele competing against wild-type, f 0 is the fraction of this allele at generation zero, s is its selection coefficient, and n is the number of generations. Note that if s > 0, as n increases, f/f 0 increases exponentially; however, given a finite population size, this value will plateau at fixation (i.e., complete takeover of the competing allele). Similarly, if s < 0, wild-type would be fixated.

Original languageEnglish
Pages (from-to)671-671
Number of pages1
JournalProtein Science
Volume28
Issue number3
Early online date12 Feb 2019
DOIs
Publication statusPublished - Mar 2019

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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