Gating of GIRK channels: Details of an intricate, membrane-delimited signaling complex

R Sadja, N Alagem, Eitan Reuveny

Research output: Contribution to journalReview articlepeer-review

90 Citations (Scopus)

Abstract

G protein-coupled inwardly rectifying potassium channels (GIRK/Kir3) are important elements in controlling cellular excitability. In recent years, tremendous progress has been made toward understanding various components involved in channel activation, modulation, and signaling specificity. In this review, we summarize these recent findings and attempt to put them in context with recently available structural data.

Original languageEnglish
Pages (from-to)9-12
Number of pages4
JournalNeuron
Volume39
Issue number1
DOIs
Publication statusPublished - 3 Jul 2003

All Science Journal Classification (ASJC) codes

  • General Neuroscience

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