How Do Cells Sense Foreign DNA? A New Outlook on the Function of STING

David Wallach; Andrew Kovalenko

doi:10.1016/j.molcel.2013.03.024

How Do Cells Sense Foreign DNA? A New Outlook on the Function of STING

David Wallach^*, Andrew Kovalenko

^*Corresponding author for this work

Department of Biomolecular Sciences

Research output: Contribution to journal › Short survey › peer-review

4 Citations (Scopus)

Abstract

STING, a protein mediating signaling activation by cytosolic DNA and known to act downstream of DNA sensor proteins, is shown also to bind DNA directly, raising the need to clarify the relative contributions of these distinct binding modes to DNA sensing.

Original language	English
Pages (from-to)	1-2
Number of pages	2
Journal	Molecular Cell
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/j.molcel.2013.03.024
Publication status	Published - 11 Apr 2013

All Science Journal Classification (ASJC) codes

Molecular Biology
Cell Biology

Access to Document

10.1016/j.molcel.2013.03.024

Cite this

@article{280edf5aea064c9d846d7909b4710eb3,

title = "How Do Cells Sense Foreign DNA? A New Outlook on the Function of STING",

abstract = "STING, a protein mediating signaling activation by cytosolic DNA and known to act downstream of DNA sensor proteins, is shown also to bind DNA directly, raising the need to clarify the relative contributions of these distinct binding modes to DNA sensing.",

author = "David Wallach and Andrew Kovalenko",

year = "2013",

month = apr,

day = "11",

doi = "10.1016/j.molcel.2013.03.024",

language = "English",

volume = "50",

pages = "1--2",

journal = "Molecular Cell",

issn = "1097-2765",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - How Do Cells Sense Foreign DNA? A New Outlook on the Function of STING

AU - Wallach, David

AU - Kovalenko, Andrew

PY - 2013/4/11

Y1 - 2013/4/11

N2 - STING, a protein mediating signaling activation by cytosolic DNA and known to act downstream of DNA sensor proteins, is shown also to bind DNA directly, raising the need to clarify the relative contributions of these distinct binding modes to DNA sensing.

AB - STING, a protein mediating signaling activation by cytosolic DNA and known to act downstream of DNA sensor proteins, is shown also to bind DNA directly, raising the need to clarify the relative contributions of these distinct binding modes to DNA sensing.

UR - http://www.scopus.com/inward/record.url?scp=84876079033&partnerID=8YFLogxK

U2 - 10.1016/j.molcel.2013.03.024

DO - 10.1016/j.molcel.2013.03.024

M3 - Short survey

SN - 1097-2765

VL - 50

SP - 1

EP - 2

JO - Molecular Cell

JF - Molecular Cell

IS - 1

ER -

How Do Cells Sense Foreign DNA? A New Outlook on the Function of STING

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this