Manganese Catalyzed Hydrogenation of Azo (N=N) Bonds to Amines

Uttam Kumar Das; Sayan Kar; Yehoshoa Ben-David; Yael Diskin‐Posner; David Milstein

doi:10.1002/adsc.202100440

Manganese Catalyzed Hydrogenation of Azo (N=N) Bonds to Amines

Uttam Kumar Das, Sayan Kar, Yehoshoa Ben-David, Yael Diskin‐Posner, David Milstein^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

We report the first example of homogeneously catalyzed hydrogenation of the N=N bond of azo compounds using a complex of an earth‐abundant‐metal. The hydrogenation reaction is catalyzed by a manganese pincer complex, proceeds under mild conditions, and yields amines, which makes this methodology a sustainable alternative route for the conversion of azo compounds. A plausible mechanism involving metal‐ligand cooperation and hydrazine intermediacy is proposed based on mechanistic studies.

Original language	English
Pages (from-to)	3744-3749
Number of pages	6
Journal	Advanced Synthesis & Catalysis
Volume	363
Issue number	15
Early online date	2 Jul 2021
DOIs	https://doi.org/10.1002/adsc.202100440
Publication status	Published - 3 Aug 2021

Funding

U. K. D. is thankful to Weizmann Institute of Science for the Senior Postdoctoral Fellowship. S.K. acknowledges the Sustainability and Energy Research Initiative (SAERI) of the Weizmann Institute of Science for a research fellowship. D.M. is the Israel Matz Professorial Chair of Organic Chemistry.

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Manganese Catalyzed Hydrogenation of Azo (N=N) Bonds to Amines

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