MIF- and CD74-Dependent Mechanisms

Shirly Becker-Herman; Naama Gil; Lihi Radomir; Idit Shachar

doi:10.1007/978-3-319-52354-5_1

MIF- and CD74-Dependent Mechanisms

Shirly Becker-Herman, Naama Gil, Lihi Radomir, Idit Shachar^*

^*Corresponding author for this work

Department of Systems Immunology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

CD74 is a type II cell surface protein that was previously shown to play a role in antigen presentation and as a receptor for the cytokine macrophage migration inhibitory factor (MIF). Studies from recent years demonstrate an important role for CD74 in maintenance of innate and adaptive immune cells. This chapter discusses the MIF/CD74-dependent role in regulating cell survival, metabolism, adhesion, and response to hypoxia in health and disease.

Original language	English
Title of host publication	MIF Family Cytokines in Innate Immunity and Homeostasis
Pages	1-20
Number of pages	20
ISBN (Electronic)	3319523546
DOIs	https://doi.org/10.1007/978-3-319-52354-5_1
Publication status	Published - 13 Jun 2017

Publication series

Series	Progress in Inflammation Research

Access to Document

10.1007/978-3-319-52354-5_1

Cite this

@inbook{f5a91f91d8ba4b77a9f1c175f234b9e4,

title = "MIF- and CD74-Dependent Mechanisms",

abstract = "CD74 is a type II cell surface protein that was previously shown to play a role in antigen presentation and as a receptor for the cytokine macrophage migration inhibitory factor (MIF). Studies from recent years demonstrate an important role for CD74 in maintenance of innate and adaptive immune cells. This chapter discusses the MIF/CD74-dependent role in regulating cell survival, metabolism, adhesion, and response to hypoxia in health and disease.",

author = "Shirly Becker-Herman and Naama Gil and Lihi Radomir and Idit Shachar",

year = "2017",

month = jun,

day = "13",

doi = "10.1007/978-3-319-52354-5_1",

language = "English",

isbn = "331952352X",

series = "Progress in Inflammation Research",

publisher = "Springer Nature Switzerland AG",

pages = "1--20",

booktitle = "MIF Family Cytokines in Innate Immunity and Homeostasis",

}

TY - CHAP

T1 - MIF- and CD74-Dependent Mechanisms

AU - Becker-Herman, Shirly

AU - Gil, Naama

AU - Radomir, Lihi

AU - Shachar, Idit

PY - 2017/6/13

Y1 - 2017/6/13

N2 - CD74 is a type II cell surface protein that was previously shown to play a role in antigen presentation and as a receptor for the cytokine macrophage migration inhibitory factor (MIF). Studies from recent years demonstrate an important role for CD74 in maintenance of innate and adaptive immune cells. This chapter discusses the MIF/CD74-dependent role in regulating cell survival, metabolism, adhesion, and response to hypoxia in health and disease.

AB - CD74 is a type II cell surface protein that was previously shown to play a role in antigen presentation and as a receptor for the cytokine macrophage migration inhibitory factor (MIF). Studies from recent years demonstrate an important role for CD74 in maintenance of innate and adaptive immune cells. This chapter discusses the MIF/CD74-dependent role in regulating cell survival, metabolism, adhesion, and response to hypoxia in health and disease.

U2 - 10.1007/978-3-319-52354-5_1

DO - 10.1007/978-3-319-52354-5_1

M3 - Chapter

SN - 331952352X

T3 - Progress in Inflammation Research

SP - 1

EP - 20

BT - MIF Family Cytokines in Innate Immunity and Homeostasis

ER -

MIF- and CD74-Dependent Mechanisms

Abstract

Publication series

Access to Document

Fingerprint

Cite this