miRNA activity directs stem cell commitment to a particular fate

Eran Hornstein

doi:10.4161/cc.9.20.13686

miRNA activity directs stem cell commitment to a particular fate

Eran Hornstein^*

^*Corresponding author for this work

Department of Molecular Genetics

Research output: Contribution to journal › Short survey › peer-review

6 Citations (Scopus)

Abstract

miR-155 function in the differentiation of monocyte cells uncovers one of the key features of miRNA-based regulation - to allow robust fate acquisition by repressing alternative programs. Several lines of evidence promote a general view of miRNA-based mechanisms, underlying the commitment of stem cells to a single cell fate while blocking other alternatives.

Original language	English
Pages (from-to)	4041-4042
Number of pages	2
Journal	Cell Cycle
Volume	9
Issue number	20
DOIs	https://doi.org/10.4161/cc.9.20.13686
Publication status	Published - 15 Oct 2010

All Science Journal Classification (ASJC) codes

Molecular Biology
Developmental Biology
Cell Biology

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title = "miRNA activity directs stem cell commitment to a particular fate",

abstract = "miR-155 function in the differentiation of monocyte cells uncovers one of the key features of miRNA-based regulation - to allow robust fate acquisition by repressing alternative programs. Several lines of evidence promote a general view of miRNA-based mechanisms, underlying the commitment of stem cells to a single cell fate while blocking other alternatives.",

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AB - miR-155 function in the differentiation of monocyte cells uncovers one of the key features of miRNA-based regulation - to allow robust fate acquisition by repressing alternative programs. Several lines of evidence promote a general view of miRNA-based mechanisms, underlying the commitment of stem cells to a single cell fate while blocking other alternatives.

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DO - 10.4161/cc.9.20.13686

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JO - Cell Cycle

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miRNA activity directs stem cell commitment to a particular fate

Abstract

All Science Journal Classification (ASJC) codes

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