Neural Circuits Underlying Sexually Dimorphic Innate Behaviors

Meital Oren-Suissa, Troy R. Shirangi

Research output: Contribution to journalReview articlepeer-review

Abstract

Sexually dimorphic instinctual behaviors that set females and males apart are found across animal clades. Recent studies in a variety of animal systems have provided deep insights into the neural circuits that guide sexually dimorphic behaviors, such as mating practices and social responses, and how sex differences in these circuits develop. Here, we discuss the neural circuits of several sexually dimorphic instinctual behaviors in rodents, flies, and worms - from mate attraction and aggression to pain perception and empathy. We highlight several salient similarities and differences between these circuits and reveal general principles that underlie the function and development of neural circuits for dimorphic behaviors.

Original languageEnglish
Pages (from-to)191-210
Number of pages20
JournalAnnual Review of Neuroscience
Volume48
Early online date3 Mar 2025
DOIs
Publication statusPublished - 16 Jul 2025

Funding

M.O.-S. is supported by the European Research Council ERC-2019-STG 850784, ERC-2024-COG 101169837, Israel Science Foundation grant 961/21, Dr. Barry Sherman Institute for Medicinal Chemistry, Sagol Weizmann-MIT Bridge Program, the Azrieli Foundation, and the Swiss Society Center for Research on Perception and Action. M.O.-S. is the incumbent of the Jenna and Julia Birnbach Family Career Development Chair. T.R.S. is supported by the National Science Foundation (IOS-1845673).

All Science Journal Classification (ASJC) codes

  • General Neuroscience

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