Perceptual stability reflected in neuronal pattern similarities in human visual cortex

Rotem Broday-Dvir; Yitzhak Norman; Michal Harel; Ashesh D. Mehta; Rafael Malach

doi:10.1016/j.celrep.2023.112614

Perceptual stability reflected in neuronal pattern similarities in human visual cortex

Rotem Broday-Dvir, Yitzhak Norman, Michal Harel, Ashesh D. Mehta, Rafael Malach^*

^*Corresponding author for this work

Department of Brain Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The magnitude of neuronal activation is commonly considered a critical factor for conscious perception of visual content. However, this dogma contrasts with the phenomenon of rapid adaptation, in which the magnitude of neuronal activation drops dramatically in a rapid manner while the visual stimulus and the conscious experience it elicits remain stable. Here, we report that the profiles of multi-site activation patterns and their relational geometry—i.e., the similarity distances between activation patterns, as revealed using intracranial electroencephalographic (iEEG) recordings—are sustained during extended visual stimulation despite the major magnitude decrease. These results are compatible with the hypothesis that conscious perceptual content is associated with the neuronal pattern profiles and their similarity distances, rather than the overall activation magnitude, in human visual cortex.

Original language	English
Article number	112614
Number of pages	20
Journal	Cell Reports
Volume	42
Issue number	6
DOIs	https://doi.org/10.1016/j.celrep.2023.112614
Publication status	Published - 27 Jun 2023

Bibliographical note

Funding Information:
We are grateful to the patients for their kind cooperation. This work was supported by the US-Israel Binational Foundation grant 2017015 (R.M. and A.D.M.) and the CIFAR Tanenbaum Fellowship (R.M.).

Funding Information:
We are grateful to the patients for their kind cooperation. This work was supported by the US-Israel BinationalFoundation grant 2017015 (R.M. and A.D.M.) and the CIFAR Tanenbaum Fellowship (R.M.). R.M. and R.B.-D. conceived the study. R.M. and Y.N. designed the experiment. R.B.-D. analyzed the data. R.M. supervised the analysis. A.D.M. performed the surgeries and supervised the experiments and all aspects of data collection. Y.N. preprocessed the data. M.H. contributed to electrode localization. R.M. and R.B.-D. wrote and edited the paper. The authors declare no competing interests. We support inclusive, diverse, and equitable conduct of research.

Publisher Copyright:
© 2023 The Author(s)

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology

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10.1016/j.celrep.2023.112614

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title = "Perceptual stability reflected in neuronal pattern similarities in human visual cortex",

abstract = "The magnitude of neuronal activation is commonly considered a critical factor for conscious perception of visual content. However, this dogma contrasts with the phenomenon of rapid adaptation, in which the magnitude of neuronal activation drops dramatically in a rapid manner while the visual stimulus and the conscious experience it elicits remain stable. Here, we report that the profiles of multi-site activation patterns and their relational geometry—i.e., the similarity distances between activation patterns, as revealed using intracranial electroencephalographic (iEEG) recordings—are sustained during extended visual stimulation despite the major magnitude decrease. These results are compatible with the hypothesis that conscious perceptual content is associated with the neuronal pattern profiles and their similarity distances, rather than the overall activation magnitude, in human visual cortex.",

author = "Rotem Broday-Dvir and Yitzhak Norman and Michal Harel and Mehta, {Ashesh D.} and Rafael Malach",

note = "Funding Information: We are grateful to the patients for their kind cooperation. This work was supported by the US-Israel Binational Foundation grant 2017015 (R.M. and A.D.M.) and the CIFAR Tanenbaum Fellowship (R.M.). Funding Information: We are grateful to the patients for their kind cooperation. This work was supported by the US-Israel BinationalFoundation grant 2017015 (R.M. and A.D.M.) and the CIFAR Tanenbaum Fellowship (R.M.). R.M. and R.B.-D. conceived the study. R.M. and Y.N. designed the experiment. R.B.-D. analyzed the data. R.M. supervised the analysis. A.D.M. performed the surgeries and supervised the experiments and all aspects of data collection. Y.N. preprocessed the data. M.H. contributed to electrode localization. R.M. and R.B.-D. wrote and edited the paper. The authors declare no competing interests. We support inclusive, diverse, and equitable conduct of research. Publisher Copyright: {\textcopyright} 2023 The Author(s)",

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Perceptual stability reflected in neuronal pattern similarities in human visual cortex

Abstract

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