Phosphorylation and Dephosphorylation of the RIG-I-like Receptors: A Safety Latch on a Fateful Pathway

David Wallach; Andrew Kovalenko

doi:10.1016/j.immuni.2013.02.014

Phosphorylation and Dephosphorylation of the RIG-I-like Receptors: A Safety Latch on a Fateful Pathway

David Wallach^*, Andrew Kovalenko

^*Corresponding author for this work

Department of Biomolecular Sciences

Research output: Contribution to journal › Short survey › peer-review

15 Citations (Scopus)

Abstract

Activation of antiviral responses by RNA sensors RIG-I and MDA5 must be stringently controlled. In this issue of Immunity, Wies et al. (2013) show that a requirement for activation-induced dephosphorylation of these proteins reinforces this restriction.

Original language	English
Pages (from-to)	402-403
Number of pages	2
Journal	Immunity
Volume	38
Issue number	3
DOIs	https://doi.org/10.1016/j.immuni.2013.02.014
Publication status	Published - 21 Mar 2013

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2013.02.014

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title = "Phosphorylation and Dephosphorylation of the RIG-I-like Receptors: A Safety Latch on a Fateful Pathway",

abstract = "Activation of antiviral responses by RNA sensors RIG-I and MDA5 must be stringently controlled. In this issue of Immunity, Wies et al. (2013) show that a requirement for activation-induced dephosphorylation of these proteins reinforces this restriction.",

author = "David Wallach and Andrew Kovalenko",

year = "2013",

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T2 - A Safety Latch on a Fateful Pathway

AU - Wallach, David

AU - Kovalenko, Andrew

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Y1 - 2013/3/21

N2 - Activation of antiviral responses by RNA sensors RIG-I and MDA5 must be stringently controlled. In this issue of Immunity, Wies et al. (2013) show that a requirement for activation-induced dephosphorylation of these proteins reinforces this restriction.

AB - Activation of antiviral responses by RNA sensors RIG-I and MDA5 must be stringently controlled. In this issue of Immunity, Wies et al. (2013) show that a requirement for activation-induced dephosphorylation of these proteins reinforces this restriction.

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U2 - 10.1016/j.immuni.2013.02.014

DO - 10.1016/j.immuni.2013.02.014

M3 - Short survey

SN - 1074-7613

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JO - Immunity

JF - Immunity

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Phosphorylation and Dephosphorylation of the RIG-I-like Receptors: A Safety Latch on a Fateful Pathway

Abstract

All Science Journal Classification (ASJC) codes

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