Plant genome engineering from lab to field—a Keystone Symposia report

Jennifer Cable; Pamela C. Ronald; Daniel Voytas; Feng Zhang; Avraham A. Levy; Ayumu Takatsuka; Shin ichi Arimura; Steven E. Jacobsen; Seiichi Toki; Erika Toda; Caixia Gao; Jian Kang Zhu; Jens Boch; Joyce Van Eck; Magdy Mahfouz; Mariette Andersson; Eyal Fridman; Trevor Weiss; Kan Wang; Yiping Qi; Tobias Jores; Tom Adams; Rammyani Bagchi

doi:10.1111/nyas.14675

Plant genome engineering from lab to field—a Keystone Symposia report

Jennifer Cable^*, Pamela C. Ronald, Daniel Voytas, Feng Zhang, Avraham A. Levy, Ayumu Takatsuka, Shin ichi Arimura, Steven E. Jacobsen, Seiichi Toki, Erika Toda, Caixia Gao, Jian Kang Zhu, Jens Boch, Joyce Van Eck, Magdy Mahfouz, Mariette Andersson, Eyal Fridman, Trevor Weiss, Kan Wang, Yiping QiTobias Jores, Tom Adams, Rammyani Bagchi

^*Corresponding author for this work

Department of Plant and Environmental Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Facing the challenges of the world's food sources posed by a growing global population and a warming climate will require improvements in plant breeding and technology. Enhancing crop resiliency and yield via genome engineering will undoubtedly be a key part of the solution. The advent of new tools, such as CRIPSR/Cas, has ushered in significant advances in plant genome engineering. However, several serious challenges remain in achieving this goal. Among them are efficient transformation and plant regeneration for most crop species, low frequency of some editing applications, and high attrition rates. On March 8 and 9, 2021, experts in plant genome engineering and breeding from academia and industry met virtually for the Keystone eSymposium “Plant Genome Engineering: From Lab to Field” to discuss advances in genome editing tools, plant transformation, plant breeding, and crop trait development, all vital for transferring the benefits of novel technologies to the field.

Original language	English
Pages (from-to)	35-54
Number of pages	20
Journal	Annals of the New York Academy of Sciences
Volume	1506
Issue number	1
Early online date	25 Aug 2021
DOIs	https://doi.org/10.1111/nyas.14675
Publication status	Published - Dec 2021

Funding

We are grateful to Ilana Agmon, who identified the semi symmetrical nature of the PTC. We also thank Ella Zimmerman, Donna Matzov, Matthew Belousoff for valuable discussions and comments; Shoshana Tel-Or, Miriam Lachever, and Maggie Kessler for their interest and experimental support; Arie Tishbee for sharing with us his MS expertise, for Zvi Hayouka and Heli Bochnic-Tamir from The Robert H Smith Faculty of Agriculture, Food and Environment for their indispensable assistance with the MALDI spectrometry. We also thank Dr. Vaijayanti A. Kumar from CSIR-National Chemical Laboratory, India, for her helpful discussion and comments on MALDI spectrometry. Funding was provided by European Research Council [Grants 322581 (NOVRIB) to A.Y.], National Institutes of Health [GM34360], The Kimmelman Center for Macromolecular Assemblies. A.Y. holds the Martin S. and Helen Kimmel Professorial Chair at the Weizmann Institute of Science. Publisher Copyright: © 2021 New York Academy of Sciences.

All Science Journal Classification (ASJC) codes

General Neuroscience
General Biochemistry,Genetics and Molecular Biology
History and Philosophy of Science

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Cite this

Cable, J., Ronald, P. C., Voytas, D., Zhang, F., Levy, A. A., Takatsuka, A., Arimura, S. I., Jacobsen, S. E., Toki, S., Toda, E., Gao, C., Zhu, J. K., Boch, J., Van Eck, J., Mahfouz, M., Andersson, M., Fridman, E., Weiss, T., Wang, K., ... Bagchi, R. (2021). Plant genome engineering from lab to field—a Keystone Symposia report. Annals of the New York Academy of Sciences, 1506(1), 35-54. https://doi.org/10.1111/nyas.14675

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abstract = "Facing the challenges of the world's food sources posed by a growing global population and a warming climate will require improvements in plant breeding and technology. Enhancing crop resiliency and yield via genome engineering will undoubtedly be a key part of the solution. The advent of new tools, such as CRIPSR/Cas, has ushered in significant advances in plant genome engineering. However, several serious challenges remain in achieving this goal. Among them are efficient transformation and plant regeneration for most crop species, low frequency of some editing applications, and high attrition rates. On March 8 and 9, 2021, experts in plant genome engineering and breeding from academia and industry met virtually for the Keystone eSymposium “Plant Genome Engineering: From Lab to Field” to discuss advances in genome editing tools, plant transformation, plant breeding, and crop trait development, all vital for transferring the benefits of novel technologies to the field.",

author = "Jennifer Cable and Ronald, {Pamela C.} and Daniel Voytas and Feng Zhang and Levy, {Avraham A.} and Ayumu Takatsuka and Arimura, {Shin ichi} and Jacobsen, {Steven E.} and Seiichi Toki and Erika Toda and Caixia Gao and Zhu, {Jian Kang} and Jens Boch and {Van Eck}, Joyce and Magdy Mahfouz and Mariette Andersson and Eyal Fridman and Trevor Weiss and Kan Wang and Yiping Qi and Tobias Jores and Tom Adams and Rammyani Bagchi",

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Cable, J, Ronald, PC, Voytas, D, Zhang, F, Levy, AA, Takatsuka, A, Arimura, SI, Jacobsen, SE, Toki, S, Toda, E, Gao, C, Zhu, JK, Boch, J, Van Eck, J, Mahfouz, M, Andersson, M, Fridman, E, Weiss, T, Wang, K, Qi, Y, Jores, T, Adams, T & Bagchi, R 2021, 'Plant genome engineering from lab to field—a Keystone Symposia report', Annals of the New York Academy of Sciences, vol. 1506, no. 1, pp. 35-54. https://doi.org/10.1111/nyas.14675

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AU - Andersson, Mariette

AU - Fridman, Eyal

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Plant genome engineering from lab to field—a Keystone Symposia report

Abstract

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