Protein degradation: BAGging up the trash

Tslil Ast; Maya Schuldiner

doi:10.1016/j.cub.2011.08.018

Protein degradation: BAGging up the trash

Tslil Ast, Maya Schuldiner^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

5 Citations (Scopus)

Abstract

Cells efficiently uncover and degrade proteins that are misfolded. However, we know very little about what cells do to protect themselves from mislocalized proteins. A new study reveals a novel quality control pathway that recognizes and degrades secretory pathway proteins that have failed to target to the endoplasmic reticulum.

Original language	English
Pages (from-to)	R692-R695
Journal	Current Biology
Volume	21
Issue number	18
DOIs	https://doi.org/10.1016/j.cub.2011.08.018
Publication status	Published - 27 Sept 2011

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1016/j.cub.2011.08.018

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@article{76b0da565d9c421d8e9841070b7c359b,

title = "Protein degradation: BAGging up the trash",

abstract = "Cells efficiently uncover and degrade proteins that are misfolded. However, we know very little about what cells do to protect themselves from mislocalized proteins. A new study reveals a novel quality control pathway that recognizes and degrades secretory pathway proteins that have failed to target to the endoplasmic reticulum.",

author = "Tslil Ast and Maya Schuldiner",

year = "2011",

month = sep,

day = "27",

doi = "10.1016/j.cub.2011.08.018",

language = "English",

volume = "21",

pages = "R692--R695",

journal = "Current Biology",

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TY - JOUR

T1 - Protein degradation

T2 - BAGging up the trash

AU - Ast, Tslil

AU - Schuldiner, Maya

PY - 2011/9/27

Y1 - 2011/9/27

N2 - Cells efficiently uncover and degrade proteins that are misfolded. However, we know very little about what cells do to protect themselves from mislocalized proteins. A new study reveals a novel quality control pathway that recognizes and degrades secretory pathway proteins that have failed to target to the endoplasmic reticulum.

AB - Cells efficiently uncover and degrade proteins that are misfolded. However, we know very little about what cells do to protect themselves from mislocalized proteins. A new study reveals a novel quality control pathway that recognizes and degrades secretory pathway proteins that have failed to target to the endoplasmic reticulum.

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U2 - 10.1016/j.cub.2011.08.018

DO - 10.1016/j.cub.2011.08.018

M3 - Short survey

SN - 0960-9822

VL - 21

SP - R692-R695

JO - Current Biology

JF - Current Biology

IS - 18

ER -

Protein degradation: BAGging up the trash

Abstract

All Science Journal Classification (ASJC) codes

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