Rapid assessment of correlated amino acids from pair-to-pair (P2P) substitution matrices

Eran Eyal*, Shmuel Pietrokovski, Ivet Bahar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Identification of correlated amino acids in proteins has been a topic of broad interest in view of its functional implications and importance in protein design. A new set of pair-to-pair (P2P) substitution matrices for amino acids was recently introduced as a useful tool for inferring information on such correlated sites. We present a website developed for automated application of these matrices for analysis of query sequences. The site offers options for graphical analysis of correlations, as well as visualization of correlated amino acids on representative, structurally characterized, members of the examined family of sequences.

Original languageEnglish
Pages (from-to)1837-1839
Number of pages3
JournalBioinformatics
Volume23
Issue number14
DOIs
Publication statusPublished - 15 Jul 2007

All Science Journal Classification (ASJC) codes

  • Computational Mathematics
  • Molecular Biology
  • Biochemistry
  • Statistics and Probability
  • Computer Science Applications
  • Computational Theory and Mathematics

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