Sperm guidance in mammals - An unpaved road to the egg

Michael Eisenbach; Laura C. Giojalas

doi:10.1038/nrm1893

Sperm guidance in mammals - An unpaved road to the egg

Michael Eisenbach^*, Laura C. Giojalas

^*Corresponding author for this work

Department of Biomolecular Sciences

Research output: Contribution to journal › Review article › peer-review

423 Citations (Scopus)

Abstract

Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells enter the Fallopian tube, and these few must be guided to make the remaining long, obstructed way to the egg. Here, we review the mechanisms by which mammalian sperm cells are guided to the egg.

Original language	English
Pages (from-to)	276-285
Number of pages	10
Journal	Nature Reviews Molecular Cell Biology
Volume	7
Issue number	4
DOIs	https://doi.org/10.1038/nrm1893
Publication status	Published - Apr 2006

All Science Journal Classification (ASJC) codes

Molecular Biology
Cell Biology

Access to Document

10.1038/nrm1893

Cite this

@article{fa5c1d6e02014fd0b2b05d9e569a3695,

title = "Sperm guidance in mammals - An unpaved road to the egg",

abstract = "Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells enter the Fallopian tube, and these few must be guided to make the remaining long, obstructed way to the egg. Here, we review the mechanisms by which mammalian sperm cells are guided to the egg.",

author = "Michael Eisenbach and Giojalas, {Laura C.}",

year = "2006",

month = apr,

doi = "10.1038/nrm1893",

language = "English",

volume = "7",

pages = "276--285",

journal = "Nature Reviews Molecular Cell Biology",

issn = "1471-0072",

publisher = "Nature Publishing Group",

number = "4",

}

TY - JOUR

T1 - Sperm guidance in mammals - An unpaved road to the egg

AU - Eisenbach, Michael

AU - Giojalas, Laura C.

PY - 2006/4

Y1 - 2006/4

N2 - Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells enter the Fallopian tube, and these few must be guided to make the remaining long, obstructed way to the egg. Here, we review the mechanisms by which mammalian sperm cells are guided to the egg.

AB - Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells enter the Fallopian tube, and these few must be guided to make the remaining long, obstructed way to the egg. Here, we review the mechanisms by which mammalian sperm cells are guided to the egg.

UR - http://www.scopus.com/inward/record.url?scp=33645756342&partnerID=8YFLogxK

U2 - 10.1038/nrm1893

DO - 10.1038/nrm1893

M3 - Review article

SN - 1471-0072

VL - 7

SP - 276

EP - 285

JO - Nature Reviews Molecular Cell Biology

JF - Nature Reviews Molecular Cell Biology

IS - 4

ER -

Sperm guidance in mammals - An unpaved road to the egg

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this