Abstract
Real-time vibrational microscopy has been recently demonstrated by various techniques, most of them utilizing the well-known schemes of coherent anti-stokes Raman scattering and stimulated Raman scattering. These techniques readily provide valuable chemical information mostly in the higher vibrational frequency regime (>400 cm(-1)). Addressing the low vibrational frequency regime (<200 cm−1 ) is challenging due to the usage of spectral filters that are required to isolate the signal from the Rayleigh scattered excitation field. In this Letter, we report on rapid, high-resolution, low-frequency (<130 cm−1 ) vibrational microscopy using impulsive coherent Raman excitation. By combining impulsive excitation with a fast acousto-optic delay line, we detect the Raman-induced optical Kerr lensing and spectral shift effects with a 25 μs pixel dwell time to produce shot-noise limited, low-frequency hyper-spectral images of various samples.
| Original language | English |
|---|---|
| Pages (from-to) | 5153-5156 |
| Number of pages | 4 |
| Journal | Optics Letters |
| Volume | 44 |
| Issue number | 21 |
| DOIs | |
| Publication status | Published - 1 Nov 2019 |
Funding
Centre National de la Recherche Scientifique (A-M-AAP-ID-17-13-170228- 15.22-RIGNEAULT, ANR-11-IDEX-0001-02); ANR grants France Bio Imaging (ANR- 10-INSB-04-01); France Life Imaging (ANR-11-INSB-0006); Plan cancer INSERM (18CP128-00, PC201508); Israeli Centers for Research Excellence; Israeli Ministry of Science Tashtiot Program (712845); CNRS-Weizmann ImagiNano European Associated Laboratory. The authors would like to thank Yahel Soffer for the sample preparation. The authors would like to thank Yahel Soffer for the sample preparation.
All Science Journal Classification (ASJC) codes
- Atomic and Molecular Physics, and Optics