The microbiome for clinicians

Serena Porcari; Siew C. Ng; Laurence Zitvogel; Harry Sokol; Rinse K. Weersma; Eran Elinav; Antonio Gasbarrini; Giovanni Cammarota; Herbert Tilg; Gianluca Ianiro

doi:10.1016/j.cell.2025.04.016

The microbiome for clinicians

Serena Porcari, Siew C. Ng, Laurence Zitvogel, Harry Sokol, Rinse K. Weersma, Eran Elinav, Antonio Gasbarrini, Giovanni Cammarota, Herbert Tilg, Gianluca Ianiro^*

^*Corresponding author for this work

Department of Systems Immunology

Research output: Contribution to journal › Review article › peer-review

7 Citations (Scopus)

Abstract

Despite promising evidence in diagnostics and therapeutics, microbiome research is not yet implemented into clinical medicine. Several initiatives, including the standardization of microbiome research, the refinement of microbiome clinical trial design, and the development of communication between microbiome researchers and clinicians, are crucial to move microbiome science toward clinical practice.

Original language	English
Pages (from-to)	2836-2844
Number of pages	9
Journal	Cell
Volume	188
Issue number	11
DOIs	https://doi.org/10.1016/j.cell.2025.04.016
Publication status	Published - 29 May 2025

Funding

G.I. was supported by the Ricerca Finalizzata Giovani Ricercatori 2018 (project GR-2018-12365734) and by the PNRR 2023 (project PNRR-POC-2023-12377319) of the Italian Ministry of Health; by the Next Gen Clinician Scientist 2024 of the AIRC (project 30203); and by the Fondo Italiano per la Scienza of the Italian Ministry of Research (project FIS00001711). The staff of the Fondazione Policlinico Gemelli IRCCS thank the Fondazione Roma for the invaluable support to their scientific research and are supported by the Ricerca Corrente 2024 of the Italian Ministry of Health. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology

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10.1016/j.cell.2025.04.016Licence: CC BY

Cite this

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title = "The microbiome for clinicians",

abstract = "Despite promising evidence in diagnostics and therapeutics, microbiome research is not yet implemented into clinical medicine. Several initiatives, including the standardization of microbiome research, the refinement of microbiome clinical trial design, and the development of communication between microbiome researchers and clinicians, are crucial to move microbiome science toward clinical practice.",

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AU - Porcari, Serena

AU - Ng, Siew C.

AU - Zitvogel, Laurence

AU - Sokol, Harry

AU - Weersma, Rinse K.

AU - Elinav, Eran

AU - Gasbarrini, Antonio

AU - Cammarota, Giovanni

AU - Tilg, Herbert

AU - Ianiro, Gianluca

PY - 2025/5/29

Y1 - 2025/5/29

N2 - Despite promising evidence in diagnostics and therapeutics, microbiome research is not yet implemented into clinical medicine. Several initiatives, including the standardization of microbiome research, the refinement of microbiome clinical trial design, and the development of communication between microbiome researchers and clinicians, are crucial to move microbiome science toward clinical practice.

AB - Despite promising evidence in diagnostics and therapeutics, microbiome research is not yet implemented into clinical medicine. Several initiatives, including the standardization of microbiome research, the refinement of microbiome clinical trial design, and the development of communication between microbiome researchers and clinicians, are crucial to move microbiome science toward clinical practice.

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U2 - 10.1016/j.cell.2025.04.016

DO - 10.1016/j.cell.2025.04.016

M3 - Review article

AN - SCOPUS:105005958016

SN - 0092-8674

VL - 188

SP - 2836

EP - 2844

JO - Cell

JF - Cell

IS - 11

ER -

The microbiome for clinicians

Abstract

Funding

All Science Journal Classification (ASJC) codes

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