Abstract
Learning and memory are two of the most magical capabilities of our mind. Learning is the biological process of acquiring new knowledge about the world, and memory is the process of retaining and reconstructing that knowledge over time. Most of our knowledge of the world and most of our skills are not innate but learned. Thus, we are who we are in large part because of what we have learned and what we remember and forget. In this Review, we examine the molecular, cellular, and circuit mechanisms that underlie how memories are made, stored, retrieved, and lost.
| Original language | English |
|---|---|
| Pages (from-to) | 163-186 |
| Number of pages | 24 |
| Journal | Cell |
| Volume | 157 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 27 Mar 2014 |
Funding
Howard Hughes Medical Institute; Center of Research Excellence in the Cognitive Sciences (I-CORE) of the Planning and Grants Committee; Israeli Science Foundation [51/11]; EP7 Human Brain Project; NIMH; NIDAWe thank the following colleagues for critical reading of this manuscript: Cristina Alberini, Tom Abrams, Craig Bailey, Blair Burns Potter, Cliff Kentros, Kelsey Martin, Richard Morris, Morris Moscovitch, and Alcino Silva. Thanks to Pauline Henick and Christina Doyle for typing and organizing the various versions of this review. E.R.K. is supported by the Howard Hughes Medical Institute. Y.D. is supported by the Center of Research Excellence in the Cognitive Sciences (I-CORE) of the Planning and Grants Committee and Israeli Science Foundation (Grant 51/11) and by the EP7 Human Brain Project. M.R.M. is supported by grants from NIMH and NIDA.
All Science Journal Classification (ASJC) codes
- General Biochemistry,Genetics and Molecular Biology